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. 2021 Oct 28;22(21):11699. doi: 10.3390/ijms222111699

Figure 8.

Figure 8

Photos of immunohistochemistry of 8-hydroxydeoxyguanosine (8-OHDG) (A). CR6-interacting factor-1 knockout (CRIF1-KO) mice had a significant increase in 8-OHDG-positive cell recruitment compared with wild-type (WT) mice. CRIF1-KO-unilateral ureteral obstruction (UUO) kidneys showed higher recruitment of 8-OHDG-positive cells than WT-UUO kidneys (B). Urinary 8-OHDG excretion in WT and CRIF1-KO mice (C). CRIF1-KO mice had a significant increase in urinary 8-OHDG compared with WT mice. CRIF1-KO-UUO kidneys showed higher urinary 8-OHDG than WT-UUO kidneys. $ p < 0.05, WT-sham vs. CRIF1-KO-sham; * p < 0.05, WT-sham vs. WT-UUO; # p < 0.05, WT-UUO vs. CRIF1-KO-UUO.