Table 1.
Baseline parameters in wild-type and CR6-interacting factor-1 knockout mice.
| WT | CRIF1-KO | p Value | |
|---|---|---|---|
| Arterial blood | |||
| pH | 7.22 (±0.06) | 7.18 (±0.01) | ns |
| Pco2(mmHg) | 47.80 (±11.48) | 54.33 (±1.53) | ns |
| HCO3-(mEq/L) | 19.26 (2.29) | 20.47 (±0.83) | ns |
| Serum | |||
| Urea Nitrogen (mg/dL) | 12.10 (±1.29) | 10.90 (±1.43) | ns |
| Creatinine (mg/dL) | 0.04 (±0.02) | 0.03 (±0.03) | ns |
| Na (mEq/L) | 142.8 (±2.37) | 150.6(4±8.82) | ns |
| K (mEq/L) | 3.6 (±0.31) | 3.9 (±0.63) | ns |
| Cl (mEq/L) | 93.1 (±2.04) | 98 (±6.34) | ns |
| Urine | |||
| 24 h Urine Volume(ml/g.bwt) | 0.059 (± 0.021) | 0.065 (±0.017) | ns |
| Urea Nitrogen (mg/dL) | 522.44 (±207.0) | 298.04 (±173.69) | ns |
| Creatinine (mg/dL) | 9.65 (±40.77) | 6.10 (±3.24) | ns |
| Na (mEq/L) | 32.04 (±7.51) | 21.82 (±11.95) | ns |
| K (mEq/L) | 35.68 (±14.87) | 17.34 (±12.42) | ns |
| Cl (mEq/L) | 32.52 (±10.11) | 18.82 (±15.53) | ns |
| ACR | 60.1 (±30.08) | 81.3 (±16.53) | ns |