Table 2.
Summary of the six noncommercial radiochemistry facilities in the UK that produce radiotracers for human use from radionuclides produced in a cyclotron. This includes their cyclotron capabilities and the radiotracers they can currently produce for human use under their manufacturer ‘specials’ licence or manufacturer licence for investigational medicinal products
| Cyclotron | Radionuclide capabilities | 18F-labelled radiotracers | 11C-labelled radiotracers | MHRA Licences | |
|---|---|---|---|---|---|
| Centre for Radiopharmaceutical Chemistry | No | NA | [18F]MK6240 | – | MS |
| [18F]DPA-714 | MIA(IMP) | ||||
| University College London | [18F]FDOPA | ||||
| [18F]D4- Fluoro –choline | |||||
| [18F]FPIA | |||||
| [18F]NAV4694 | |||||
| Positron Emitting Radiopharmaceutical Laboratory | Yes | Fluorine-18 | [18F]FDG | – | MS |
| Carbon-11 | MIA(IMP) | ||||
| King’s College London | Oxygen-15 | ||||
| Nitrogen-13 | |||||
| Copper-64 | |||||
| Wolfson Brain Imaging Centre | Yes | Fluorine-18 | [18F]FLT | [11C]Acetate | MS |
| Carbon-11 | [18F]FMISO | [11C]Methionine | MIA(IMP) | ||
| University of Cambridge | Oxygen-15 | [18F]GE-226 | [11C]Metomidate | ||
| Copper-64 | [18F]AV-1451 | [11C]Leucine | |||
| [18F]CETO | [11C]PIB | ||||
| [18F]FDOPA | [11C]PK11195 | ||||
| [11C]UCB-J | |||||
| Wales Research and Diagnostic PET Imaging Centre | Yes | Fluorine-18 | [18F]FDG | – | MS |
| Carbon-11 | [18F]F-PSMA-1007 | ||||
| Cardiff University | Oxygen-15 | [18F]Fallypride | |||
| Nitrogen-13 | [18F]FDOPA | ||||
| Gallium-68 | [18F]Flumazenil | ||||
| Zirconium-89 | |||||
| Vanadium-48 | |||||
| Edinburgh Imaging | Yes | Fluorine-18 | [18F]FDG | – | MS |
| Carbon-11 | [18F]Fluoro-choline | MIA(IMP) | |||
| University of Edinburgh | Oxygen-15 | [18F]NaF | |||
| [18F]GP1 | |||||
| [18F]Flutemetamol | |||||
| West of Scotland PET Centre | Yes | Fluorine-18 | [18F]FDG | – | MS |
| Carbon-11 | [18F]FMISO | MIA(IMP) | |||
| NHS Greater Glasgow and Clyde |