Table 3.

Fatty acid composition in the cortex, hippocampus, and liver of mice after 8-week NL treatment. The values are expressed as the mean ± SD. Statistical differences between the control and nanoliposome groups for each fatty acid are shown for each tissue (* p < 0.05, ** p < 0.01, *** p < 0.001).

	Cortex		Hippocampus		Liver
Fatty Acids (mg/g Dry Tissue)	C	NL	C	NL	C	NL
C10:0	0.18 ± 0.04	0.44 ± 0.06 *	0.44 ± 0.19	0.35 ± 0.05	-	-
C12:0	0.10 ± 0.02	0.25 ± 0.04 *	0.19 ± 0.03	0.22 ± 0.04	-	-
C14:0	0.45 ± 0.10	1.09 ± 0.12 **	0.61 ± 0.05	0.90 ± 0.19	0.16 ± 0.01	0.14 ± 0.03
C16:0	6.16 ± 1.18	16.30 ± 2.70 *	12.99 ± 1.91	14.61 ± 3.27	12.52 ± 1.56	10.24 ± 2.14
C18:0	6.03 ± 1.17	15.58 ± 1.92 **	12.75 ± 1.71	14.31 ± 2.65	5.53 ± 0.67	4.87 ± 1.01
C20:0	0.08 ± 0.01	0.25 ± 0.01 ***	0.17 ± 0.01	0.23 ± 0.07	0.29 ± 0.03	0.28 ± 0.07
Saturated	13.00 ± 2.51	33.91 ± 4.82 **	27.15 ± 3.73	30.62 ± 6.27	18.50 ± 2.27	15.53 ± 3.14
C14:1	0.36 ± 0.08	0.78 ± 0.05 **	0.33 ± 0.16	0.46 ± 0.08	-	-
C14:1n-9	0.29 ± 0.06	0.68 ± 0.07 **	0.29 ± 0.25	0.58 ± 0.10	-	-
C16:1	0.10 ± 0.01	0.36 ± 0.02 ***	0.49 ± 0.21	0.39 ± 0.13	-	-
C16:1n-9	0.14 ± 0.02	0.44 ± 0.14	0.34 ± 0.04	0.44 ± 0.18	0.16 ± 0.01	0.15 ± 0.04
C16:1n-7	0.23 ± 0.05	0.66 ± 0.06 **	0.21 ± 0.11	0.44 ± 0.08	0.99 ± 0.12	0.85 ± 0.27
C18:1n-9	3.94 ± 0.93	10.45 ± 2.10 *	8.09 ± 0.98	10.19 ± 2.68	5.76 ± 0.08	4.98 ± 1.17
C18:1n-7	0.88 ± 0.19	2.03 ± 0.54	1.53 ± 0.13	1.88 ± 0.52	1.13 ± 0.03	0.95 ± 0.19
C20:1n-9	0.07 ± 0.02	0.28 ± 0.02 **	0.14 ± 0.01	0.28 ± 0.11	0.69 ± 0.16	0.56 ± 0.16
C22:1n-9	0.40 ± 0.12	1.01 ± 0.11 **	0.72 ± 0.11	0.88 ± 0.19	-	-
Monounsaturated	6.41 ± 1.45	16.69 ± 2.71 *	12.14 ± 0.96	15.54 ± 3.92	8.73 ± 0.40	7.49 ± 1.80
C18:2n-6	0.45 ± 0.11	1.20 ± 0.56	1.21 ± 0.17	1.71 ± 0.82	6.34 ± 0.67	5.66 ± 1.06
C18:3n-6	0.07 ± 0.01	0.18 ± 0.01 **	0.20 ± 0.04	0.22 ± 0.05	0.09 ± 0.02	0.07 ± 0.02
C20:4n-6	2.58 ± 0.51	6.59 ± 0.80 **	4.51 ± 0.05	5.89 ± 1.48	6.18 ± 0.25	4.90 ± 0.97
C22:4n-6	0.64 ± 0.14	1.61 ± 0.11 **	1.03 ± 0.09	1.34 ± 0.28	0.23 ± 0.02	0.20 ± 0.07
C22:5n-6	3.81 ± 0.72	10.67 ± 1.64 *	5.62 ± 0.43	7.65 ± 1.48	3.70 ± 1.19	3.63 ± 0.81
n-6	7.55 ± 1.48	20.25 ± 3.05 *	12.57 ± 0.78	16.81 ± 4.12	16.54 ± 2.15	14.46 ± 2.86
C18:3n-3	0.28 ± 0.08	0.72 ± 0.03 **	0.47 ± 0.07	0.53 ± 0.14	0.26 ± 0.01	0.26 ± 0.05
C20:5n-3	0.14 ± 0.05	0.33 ± 0.03 *	0.28 ± 0.08	0.33 ± 0.08	0.21 ± 0.03	0.20 ± 0.05
C22:5n-3	1.60 ± 0.38	4.21 ± 0.37 **	2.78 ± 0.22	3.60 ± 0.78	0.56 ± 0.08	0.52 ± 0.11
C22:6n-3	3.85 ± 0.92	10.20 ± 0.91 **	6.68 ± 0.53	8.66 ± 1.91	1.35 ± 0.20	1.26 ± 0.26
n-3	5.87 ± 1.42	15.47 ± 1.22 **	10.21 ± 0.89	13.12 ± 2.91	2.38 ± 0.31	2.24 ± 0.47
Polyunsaturated	13.42 ± 2.91	35.71 ± 4.26 **	22.78 ± 1.67	29.93 ± 7.03	18.92 ± 2.47	16.70 ± 3.32
n-6/n-3	1.29 ± 0.06	1.30 ± 0.10	1.23 ± 0.03	1.28 ± 0.03	6.99 ± 0.02	6.49 ± 0.25
AA/DHA	0.67 ± 0.03	0.64 ± 0.02	0.68 ± 0.05	0.68 ± 0.02	4.64 ± 0.52	3.93 ± 0.34
PUFA/SFA	1.03 ± 0.02	1.06 ± 0.04	0.84 ± 0.05	0.97 ± 0.03	1.02 ± 0.01	1.08 ± 0.07
MUFA/SFA	0.49 ± 0.02	0.49 ± 0.05	0.45 ± 0.03	0.50 ± 0.02	0.47 ± 0.04	0.48 ± 0.07