Figure 10.

Negative effect of age on whole brain WM skeleton for both scanners separately (red circles: Verio, dark red triangles: Skyra, black framed circles and triangles: randomly selected to simulate pooled dataset from two different scanners). The effect modelled with linear modelling (mean FA value ~ age) is comparable between scanners (estimate ± std. error: Verio: Verio: −3.203 × 10⁻⁴ ± 1.237 × 10⁻⁴ and Skyra: −2.957 × 10⁻⁴ ± 1.347 × 10⁻⁴, random scanner: −2.925 × 10⁻⁴ ± 1.265 × 10⁻⁴). Bayesian linear modelling delivered significant results for the negative age effect: $BF\left[\frac{mean FA value\sim age \times scanner}{mean FA value\sim scanner}\right]$ = 5.49 ± 1.39%. In the case of studies conducted on different scanners (simulated by randomly selected subjects from Skyra and Verio, black line), the age effect size was still present and of intermediate magnitude.