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. 2021 Nov 2;10(21):5144. doi: 10.3390/jcm10215144

Table 3.

Comparison of clinicopathological characteristics between patients with multifocal PTCs and those with unifocal tumor after propensity score matching.

Characteristics Univariate Analysis Multivariate Analysis
HR (95% CI) p-Value HR (95% CI) p-Value
 Age (years) 0.982 (0.952–1.012) 0.239
 Male sex 2.974 (1.433–6.170) 0.003 2.185 (1.047–4.559) 0.037
 Tumor size (cm) 2.340 (1.833–2.987) <0.001 1.806 (1.337–2.441) <0.001
 Microscopic ETE 2.708 (1.186–6.182) 0.018 1.311 (0.551–3.122) 0.541
 LN metastasis
  N1a 3.858 (1.587–9.380) 0.003 1.859 (0.677–5.102) 0.229
  N1b 12.704 (5.066–31.857) <0.001 3.603 (1.207–10.757) 0.022
 Margin involvement 2.071 (0.497–8.628) 0.317
 Hashimoto thyroiditis 0.643 (0.282–1.467) 0.294
131I remnant ablation 6.512 (2.709–15.656) <0.001 2.345 (0.807–6.811) 0.117
 Multifocality 2.294 (1.183–4.451) 0.014 1.986 (1.015–3.888) 0.045

HR, hazard ratio; CI, confidence interval; ETE, extrathyroidal extension; LN, lymph node.