Table 6.
Comparison of ghrelin, obestatin, and leptin levels depending on the severity of esophagitis (statistically significant correlations, where p < 0.05, are marked using *).
| Laboratory Parameters | The Severity of Inflammatory Changes in the Esophagus–Gastroscopy Assessment |
p | |||||
|---|---|---|---|---|---|---|---|
| 0–1 pts (N = 24) | 2–3 pts (N = 8) | ||||||
| Mean | Median | IQR | Mean | Median | IQR | ||
| Ghrelin at 23 (pg/mL) | 452.7 | 412.1 | 250.4 | 735.9 | 604.0 | 345.5 | 0.0943 |
| Ghrelin at 1 (pg/mL) | 391.2 | 345.0 | 231.1 | 670.1 | 534.6 | 366.2 | 0.0328 * |
| Ghrelin at 3 (pg/mL) | 413.3 | 388.6 | 229.0 | 702.9 | 485.3 | 364.9 | 0.1354 |
| Ghrelin at 5 (pg/mL) | 404.1 | 372.4 | 234.4 | 660.5 | 464.5 | 387.4 | 0.1241 |
| Ghrelin at 7 (pg/mL) | 423.3 | 384.4 | 227.1 | 697.3 | 518.0 | 281.7 | 0.0515 |
| Ghrelin (mean) (pg/mL) | 416.9 | 404.1 | 220.1 | 693.3 | 518.5 | 342.0 | 0.0572 |
| Leptin at 23 (ng/mL) | 32.1 | 30.0 | 18.0 | 30.0 | 28.3 | 7.3 | 0.9635 |
| Leptin at 1 (ng/mL) | 29.6 | 26.3 | 10.8 | 28.7 | 26.9 | 6.0 | 0.9023 |
| Leptin at 3 (ng/mL) | 29.8 | 24.9 | 13.0 | 29.2 | 28.1 | 5.6 | 0.7120 |
| Leptin at 5 (ng/mL) | 29.8 | 28.7 | 12.8 | 28.8 | 28.1 | 4.3 | 0.9635 |
| Leptin at 7 (ng/mL) | 30.2 | 31.1 | 9.6 | 29.2 | 29.3 | 4.4 | 0.6977 |
| Leptin (mean) (ng/mL) | 30.1 | 26.5 | 13.4 | 29.3 | 28 | 5.5 | 0.7743 |
| Obestatin at 23 (pg/mL) | 59.0 | 56.6 | 7.0 | 59.6 | 60.2 | 5.6 | 0.6167 |
| Obestatin at 1 (pg/mL) | 71.0 | 69.5 | 9.0 | 68.6 | 68.9 | 3.2 | 0.6521 |
| Obestatin at 3 (pg/mL) | 67.6 | 66.6 | 8.7 | 65.7 | 66.4 | 7.3 | 0.8375 |
| Obestatin at 5 (pg/mL) | 60.9 | 59.6 | 9.6 | 60.0 | 60.0 | 0.4 | 0.7505 |
| Obestatin at 7 (pg/mL) | 59.8 | 59.3 | 8.4 | 58.6 | 59.8 | 3.1 | 0.8916 |
| Obestatin (mean) (pg/mL) | 65.7 | 62.5 | 9.2 | 62.5 | 62.9 | 2.0 | 0.8375 |