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. 2021 Oct 31;22(21):11829. doi: 10.3390/ijms222111829
AEs adverse events
ALK anaplastic lymphoma kinase
AST aspartate aminotransferase
ATA American Thyroid Association
ATC anaplastic thyroid cancer
BMI body mass index
BRAF B-Raf proto-oncogene
CT computer tomography
CTLA-4 cytotoxic T-lymphocyte antigen-4
DeTC dedifferentiated thyroid cancer
DIT diiodotyrosine
DTC differentiated thyroid cancer
EBRT external beam radiation therapy
eIF1A eukaryotic translation initiation factor 1A
EMA European Medical Agency
FAP familial adenomatous polyposis
FDA Food and Drug Administration
18FDG 18F-fluoro-2-deoxy-D-glucose
FNAB fine-needle aspiration biopsy
FTC follicular thyroid carcinoma
FVPTC follicular variant of PTC
GTP guanosine triphosphate
HCC Hürtle cell carcinoma
HNHA N-hydroxy-7-(2-naphthylthio) heptanamide
HT hypertension
IDH1 isocitrate dehydrogenase 1
IDH2 isocitrate dehydrogenase 2
IMRT intensity-modulated radiation therapy
KIs kinase inhibitors
MAPK mitogen-activated protein kinase
MEN multiple endocrine neoplasia
MEN2 multiple endocrine neoplasia type 2
MIT monoiodotyrosine
MKIs multi-kinase inhibitors
MRI magnetic resonance imaging
MTC medullary thyroid cancer
ND not defined
NIS sodium iodide symporter
ORR overall response rate
OS overall survival
PAX8 paired box 8
PD progressive disease
PDCT poorly differentiated thyroid carcinoma
PET positron emission tomography
PFS progression-free survival
PI3K phosphatidylinositol 3-kinase
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase
PLC-γ phospholipase C
PPARγ peroxisome proliferator activated receptor γ
PPES palmar-plantar erythrodysesthesia syndrome
PR partial response
PTC papillary thyroid carcinoma
RAI radioactive iodine; radioiodine
RAIR radioactive iodine refractory; radioiodine refractory
RANKL receptor activator of nuclear factor κ-Β ligand
RETf RET fusion-positive
RETm RET mutation-positive
RTK receptor tyrosine kinase
RWS Real-Word Studies
SD stable disease
SKIs specific kinase inhibitors
T3 triiodothyronine
T4 thyroxine
TBSRTC The Bethesda System for Reporting Thyroid Cytopathology
TC thyroid cancer
TCGA The Cancer Genome Atlas
TERT telomerase reverse transcriptase
Tg thyroglobulin
THs thyroid hormones
TPO thyroid peroxidase
TRK tropomyosin receptor kinase
TSH thyroid-stimulating hormone
USG ultrasonography
WBC white blood cell
WHO World Health Organization
wt wild type