Table 3.

Comparison of the clinical, epidemiological, metabolic, and radiomics feature distributions between the two PET scanners.

SCANNER D690 vs. D-STE
Clinical-Epidemiological Features	p-Value	Second-Order Statistics	p-Value
Age	0.659	GLCM entropy_log10	<0.001
Gender	0.659	GLCM entropy_log2	<0.001
Size	0.746	GLCM dissimilarity	<0.001
“Conventional” PET features		GLRLM SRE	<0.001
SUVmax	<0.001	GLRLM LRE	<0.001
SUVmean	<0.001	GLRLM LGRE	0.001
SUVlbm	<0.001	GLRLM HGRE	<0.001
SUVbsa	<0.001	GLRLM SRLGE	0.002
L-L SUV R	0.003	GLRLM SRHGE	<0.001
L-BP SUV R	0.009	GLRLM LRLGE	<0.001
MTV	<0.001	GLRLM LRHGE	0.006
TLG	<0.001	GLRLM GLNU	<0.001
First-order statistics		GLRLM RLNU	0.052
Histo skewness	0.316	GLRLM RP	<0.001
Histo kurtosis	0.758	NGLDM coarseness	0.799
Histo excess kurtosis	0.758	NGLDM contrast	<0.001
Histo entropy_log10	<0.001	NGLDM busyness	<0.001
Histo entropy_log2	<0.001	GLZLM SZE	<0.001
Histo energy	<0.001	GLZLM LZE	<0.001
Shape volume_mL	0.917	GLZLM LGZE	0.003
Shape volume_vx	0.917	GLZLM HGZE	<0.001
Shape sphericity	0.037	GLZLM SZLGE	0.877
Shape compacity	0.859	GLZLM SZHGE	<0.001
Second-order statistics		GLZLM LZLGE	<0.001
GLCM homogeneity	<0.001	GLZLM LZHGE	0.002
GLCM energy	<0.001	GLZLM GLNU	0.803
GLCM contrast	< 0.001	GLZLM ZLNU	<0.001
GLCM correlation	0.052	GLZLM ZP	< 0.001