Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Nov 3;10(21):5160. doi: 10.3390/jcm10215160

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the author.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Herein, the imaging findings of a 66-year old male with metastatic NSCLC investigated before (A–C) and after 3 cycles of pembrolizumab (D–F). An overall response to treatment is easily visible on MIP (maximal intensity projection) images (C,F), including a complete metabolic remission of all bony lesions ((C); white hollowed arrow). On the contrary, morphological imaging proved the appearance of a new bone lesion in the first lumbar vertebra ((A,D); white arrows), which in fact corresponded to a healed metastasis on PET/CT (B,E). Note also the appearance of diffuse thyroid uptake ((F); red arrow), consistent with thyroiditis, one of the irAEs that typically predicts treatment response and good patient’s outcome.