Table 1.
Patient characteristics.
| Characteristics | n | % |
|---|---|---|
| Enrolled | 78 | 100 |
| Sex | ||
| Male | 43 | 55 |
| Female | 35 | 45 |
| Age, years median (range) | 64 (30–78) | |
| ECOG performance status | ||
| 0 | 22 | 28 |
| 1 | 51 | 65 |
| 2 | 5 | 6 |
| Primary site | ||
| Cecum | 7 | 9 |
| Ascending colon | 4 | 5 |
| Hepatic flexure of the large intestine | 3 | 4 |
| Transverse colon | 4 | 5 |
| Splenic flexure of the large intestine | 4 | 5 |
| Colon descending | 3 | 4 |
| Sigmoid | 17 | 22 |
| Rectosigmoid junction | 8 | 10 |
| Rectum | 28 | 36 |
| Primary tumor location | ||
| Right colon | 17 | 22 |
| Left colon | 61 | 78 |
| Primary tumor histological subtype | ||
| Adenocarcinoma | 73 | 94 |
| Mucinous adenocarcinoma | 4 | 5 |
| Signet ring cell carcinoma | 1 | 1 |
| Histological differentiation: | ||
| Well | 10 | 13 |
| Moderate | 51 | 65 |
| Poorly | 6 | 8 |
| Unknown | 11 | 14 |
| pT category | ||
| pT1 | 1 | 1 |
| pT2 | 7 | 9 |
| pT3 | 48 | 62 |
| pT4 | 17 | 22 |
| Not operated on | 5 | 6 |
| pN category | ||
| pN0 | 18 | 23 |
| pN1 | 28 | 36 |
| pN2 | 27 | 35 |
| not operated on | 5 | 6 |
| Site of metastasis | ||
| Liver | 49 | 63 |
| Lung | 19 | 24 |
| Lymph node | 18 | 23 |
| Peritoneum | 16 | 21 |
| KRAS mutation status | ||
| Wild-type | 36 | 46 |
| Mutant | 40 | 51 |
| BRAF mutation status | ||
| Wild-type | 61 | 78 |
| Mutant | 6 | 7 |
| NRAS mutation status | ||
| Wild-type | 72 | 92 |
| Mutant | 1 | 1 |
Abbreviation: ECOG Eastern Cooperative Oncology Group; pT: size or direct extent of the primary tumor given by histopathologic examination of a surgical specimen according to TNM staging system; pN: degree of spread to regional lymph nodes given by histopathologic examination of a surgical specimen.