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. 2021 Oct 28;10(21):5027. doi: 10.3390/jcm10215027

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Synovial fluid log concentration levels of cytokines, chemokines, MMPs and select protein levels from normal subjects, patients with OA, and patients with controlled rheumatoid arthritis and active rheumatoid arthritis. Panel legend: panel (a) TNF-α = Tumor Necrosis Factor alpha, panel (b) MMP-8 = Matrix Metalloproteinase 8, panel (c) MMP-2 = Matrix Metalloproteinase 2, panel (d) MMP-1 = Matrix Metalloproteinase 1, panel (e) IL-1 b = Interleukin 1 beta, panel (f) IL-7 = Interleukin 7, panel (g) IGFBP-3 = Insulin-Like Growth Factor-Binding Protein 3, panel (h) MMP-3 = Matrix Metalloproteinase 3, panel (i) IL-6 = Interleukin 6, panel (j) L-1 ra = Interleukin 1 receptor antagonist, panel (k) IGFBP-4 = Insulin-Like Growth Factor-Binding Protein 4, panel (l) IL 18 = Interleukin 18, panel (m) IL-2 = Interleukin 2, panel (n) IL-4 = Interleukin 4, panel (o) G-CSF = Granulocyte Colony Stimulating Factor, and panel (p) IL-15 = Interleukin 15.