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Angiogenesis in psoriasis: Th17 cells of psoriasis provoke angiogenesis through IL-17 production. In addition to angiogenesis promotion, expression of other angiogenic factors like VEGF and IL-8 is upregulated by IL-17. Keratinocytes, immune cells like mast cells, secrete a variety of pro-angiogenic factors and cytokines that activate and maintain the inflammatory skin condition of psoriasis.
