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. 2021 Nov 6;22(21):12029. doi: 10.3390/ijms222112029

Figure 4.

Figure 4

Effects of arachidonic acid metabolites on cardiovascular diseases. Various metabolites including prostaglandin (PG)D2 and PGE2 (to EP1, EP2, EP3 or EP4 receptor), prostacyclin (PGI2), thromboxane (TX)A2, leukotrienes B4 (LTB4) (to CysLT receptors), lipoxin A4 (LXA4), hydroxyeicosatetraenoic acids (HETEs), and epoxyeicosatrienoic acids (EETs) exert vasoprotective (labeled with blue color) and deteriorative effects (labeled with red color).