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Fluorescence titration curves were obtained by plotting the fraction of bound compound (20a in green, 23a in blue, 15c in black, and 18c in red) as a function of (a) c-Myc G4, (b) c-Myc iM, and (c) hTeloC iM concentration. Titrations were carried out in 10 mM potassium phosphate buffer (pH 5.0) for c-Myc G4, and 10 mM sodium phosphate buffer (pH 5.0) for c-Myc iM and hTeloC iM.
