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Binding constant (Kb) values were obtained by fitting the fluorescence titration curves to an independent and equivalent binding sites model [54].
| Compound | Kb (×106 M−1) 1 | ||
|---|---|---|---|
| c-Myc G4 | c-Myc iM | hTeloC iM | |
| 20a | 2.3 | 3.1 | 3.1 |
| 23a | 2.2 | 3.2 | 3.1 |
| 15c | 2.5 | 3.4 | 3.2 |
| 18c | 3.1 | 2.8 | 2.6 |
1 The error on the Kb values is ±0.2.
