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. 2021 Nov 8;22(21):12063. doi: 10.3390/ijms222112063

Figure 6.

Figure 6

Clioquinol (CQ) decreased caspase cleaved tau in M1C cells. (A) CQ decreased caspase cleaved tau on Western blot analysis. NI: non induced, 0: vehicle-treated cells, 1, and 5:1, and 5 μM CQ-treated cells. n = 4, Bar: ± SD, ** p < 0.01. (B) Analysis of TauC3 immunofluorescence signal (ratio to signal from P44, a non-phospho dependent tau antibody) showed a significant reduction following 1 μM of CQ treatment. 0: vehicle-treated cells, 1:1 μM CQ-treated cells. n = 4, Bar: 50 μm, * p < 0.05. TauC3/GAPDH followed a normal distribution and was analyzed by one-way ANOVA followed by the Bonferroni post hoc test, and the data from TOC1/P44 followed a normal distribution and were analyzed by the Student’s t-test.