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. 2021 Nov 4;22(21):11963. doi: 10.3390/ijms222111963

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Cellular functions of RBPs. RBPs are involved in post-transcriptional regulation of target mRNAs. Pre-mRNA is first transcribed from the DNA. Then, RBPs regulate the production of mature mRNA via polyadenylation (1), splicing (2), and mRNA editing (3). RBPs can also regulate mRNA stability (4) and mRNA subcellular localization (5) within the cell in SGs or P-bodies, as well as mRNA translation into proteins (6). Pre-mRNA, precursor mRNA; SGs, stress granules; P-bodies, processing-bodies. Created with BioRender.com.