Table 1.
BMMSCs | hDPSCs | SHED | DFPCs | SCAPs | GMSCs | PDLSCs | hPCy-MSCs | |
---|---|---|---|---|---|---|---|---|
Location | Bone Marrow | Permanent Tooth Pulp | Exfoliated Decidous Tooth Pulp | Dental Follcle Tissue | Apical Papilia | Gingival Tissue | Peridontal Ligament | Periaphical Cyst-Derived Mesenchymal Stem Cells |
Morphological features: | ||||||||
Shape in culture | Fibroblast-like cells | Fibroblast-like cells | Fibroblast-like cells | Fibroblast-like cells | Fibroblast-like cells | Fibroblast-like cells | Fibroblast-like cells | Fibroblast-like cells |
Adherence to surfaces | +++ | +++ | +++ | +++ | +++ | +++ | +++ | +++ |
Colony formation | ++ | +++ | +++ | +++ | +++ | +++ | +++ | +++ |
Proliferation potential | ++ | +++ | +++ | +++ | +++ | +++ | +++ | +++ |
Migration abilities | + | ++ | ++ | ++ | ++ | ++ | ++ | not done |
Heterogeneity | ++ | ++ | ++ | ++ | ++ | ++ | ++ | not done |
Clonogenic potency | ++ | +++ | +++ | +++ | +++ | ++ | +++ | +++ |
Autologous application abilities | +++ | +++ | +++ | +++ | +++ | +++ | +++ | +++ |
Immunoreactivity Positive biomarkers | CD10, CD13, CD44, CD73, CD90, CD105, CD106, CD146, CD166, STRO-1 | CD10, CD13, CD29, CD44, CD73, CD90, CD105, CD106, CD117, CD146, STRO-1 | CD13, CD29, CD44, CD73, CD90, CD105, CD106, CD146, CD166, STRO-1 | CD10, CD13, CD29, CD44, CD59, CD73, CD90, CD105, STRO-1 | CD13, CD24, CD29, CD44, CD73, CD90, CD105, CD106, CD146, CD166, STRO-1 | CD13, CD29, CD44, CD73, CD90, CD105, CD106, CD146, CD166, STRO-1, SSEA | CD10, CD13, CD26, CD29, CD44, CD59, CD73, CD90, CD105, CD106, CD140b, CD146 CD166, STRO-1, STRO-3, STRO-4, NG2 | CD13, CD29, CD44, CD73, CD90, CD105, CD146, STRO-1 |
Negative biomarkers | CD11b, CD14, CD19, CD34, CD40, CD45, CD79a, CD80, CD86, HLA-DR | CD14, CD19, CD24, CD34, CD45, HLA-DR | CD14, CD18, CD19, CD24, CD34, CD45 | CD11b, CD34, CD45, HLA-DR | CD14, CD34, CD45, CD150, HLA-DR | CD14, CD34, CD45, HLA-DR | CD11b, CD14, CD19, CD31, CD34, CD40, CD45, CD79α, CD80, CD86, HLA-DR | CD34, CD45, HLA-DR |
Multipotentialy: | ||||||||
Osteogenic— | ++ | +++ | +++ | +++ | +++ | +++ | +++ | +++ |
Chondrogenic— | ++ | +++ | +++ | ++ | ++ | +++ | ++ | not done |
Neorogenic— | ++ | +++ | +++ | +++ | +++ | +++ | +++ | +++ |
Adipogenic—differentiation | ++ | +++ | ++ | ++ | ++ | ++ | ++ | +++ |
Tissue repair, regeneration |
bone, cartilage, neurodegenerative disease, spinal cord injury, myocardial regeneration | bone, cartilage, neurodegenerative disease, spinal cord injury, peripheral nerve injury, dental tissues, corneal regeneration | bone, cartilage, neurodegenerative disease, spinal cord injury, peripheral nerve injury, diabetes mellitus | bone, cartilage, peridontal tissue, neurodegenerative disease | bone, cartilage, peridontal tissue, neurodegenerative disease | bone, cartilage, peridontal tissue, neural disorders, skin injuries | bone, cartilage, peridontal tissue, neural disorders | bone, neurogenerative disease, oeridontal tissue |
+++ high, ++ moderate, + low.