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. 2021 Nov 6;22(21):12018. doi: 10.3390/ijms222112018

Table 1.

Biological features and multipotency capacity human mesenchymal stem cells from bone marrow and dental tissues.

BMMSCs hDPSCs SHED DFPCs SCAPs GMSCs PDLSCs hPCy-MSCs
Location Bone Marrow Permanent Tooth Pulp Exfoliated Decidous Tooth Pulp Dental Follcle Tissue Apical Papilia Gingival Tissue Peridontal Ligament Periaphical Cyst-Derived Mesenchymal Stem Cells
Morphological features:
Shape in culture Fibroblast-like cells Fibroblast-like cells Fibroblast-like cells Fibroblast-like cells Fibroblast-like cells Fibroblast-like cells Fibroblast-like cells Fibroblast-like cells
Adherence to surfaces +++ +++ +++ +++ +++ +++ +++ +++
Colony formation ++ +++ +++ +++ +++ +++ +++ +++
Proliferation potential ++ +++ +++ +++ +++ +++ +++ +++
Migration abilities + ++ ++ ++ ++ ++ ++ not done
Heterogeneity ++ ++ ++ ++ ++ ++ ++ not done
Clonogenic potency ++ +++ +++ +++ +++ ++ +++ +++
Autologous application abilities +++ +++ +++ +++ +++ +++ +++ +++
Immunoreactivity Positive biomarkers CD10, CD13, CD44, CD73, CD90, CD105, CD106, CD146, CD166, STRO-1 CD10, CD13, CD29, CD44, CD73, CD90, CD105, CD106, CD117, CD146, STRO-1 CD13, CD29, CD44, CD73, CD90, CD105, CD106, CD146, CD166, STRO-1 CD10, CD13, CD29, CD44, CD59, CD73, CD90, CD105, STRO-1 CD13, CD24, CD29, CD44, CD73, CD90, CD105, CD106, CD146, CD166, STRO-1 CD13, CD29, CD44, CD73, CD90, CD105, CD106, CD146, CD166, STRO-1, SSEA CD10, CD13, CD26, CD29, CD44, CD59, CD73, CD90, CD105, CD106, CD140b, CD146 CD166, STRO-1, STRO-3, STRO-4, NG2 CD13, CD29, CD44, CD73, CD90, CD105, CD146, STRO-1
Negative biomarkers CD11b, CD14, CD19, CD34, CD40, CD45, CD79a, CD80, CD86, HLA-DR CD14, CD19, CD24, CD34, CD45, HLA-DR CD14, CD18, CD19, CD24, CD34, CD45 CD11b, CD34, CD45, HLA-DR CD14, CD34, CD45, CD150, HLA-DR CD14, CD34, CD45, HLA-DR CD11b, CD14, CD19, CD31, CD34, CD40, CD45, CD79α, CD80, CD86, HLA-DR CD34, CD45, HLA-DR
Multipotentialy:
Osteogenic— ++ +++ +++ +++ +++ +++ +++ +++
Chondrogenic— ++ +++ +++ ++ ++ +++ ++ not done
Neorogenic— ++ +++ +++ +++ +++ +++ +++ +++
Adipogenic—differentiation ++ +++ ++ ++ ++ ++ ++ +++
Tissue repair,
regeneration
bone, cartilage, neurodegenerative disease, spinal cord injury, myocardial regeneration bone, cartilage, neurodegenerative disease, spinal cord injury, peripheral nerve injury, dental tissues, corneal regeneration bone, cartilage, neurodegenerative disease, spinal cord injury, peripheral nerve injury, diabetes mellitus bone, cartilage, peridontal tissue, neurodegenerative disease bone, cartilage, peridontal tissue, neurodegenerative disease bone, cartilage, peridontal tissue, neural disorders, skin injuries bone, cartilage, peridontal tissue, neural disorders bone, neurogenerative disease, oeridontal tissue

+++ high, ++ moderate, + low.