Table 4. Multi-HTLV intensities for indeterminate samples.
Gold Standard Results | Multi-HTLV Intensity | Nb antigen with intensity > = 10 | LR for confirmation (p) | Final Result | |||
---|---|---|---|---|---|---|---|
GP21-I/II CONF | P19-I/II CONF | GP46-I/II CONF | |||||
A) Development | Negative | 6,01 | 18,77 | 15,49 | 2 | 0,06 | IND |
Negative | 36,48 | 1,23 | 1,14 | 1 | 0,84 | IND | |
B) Validation | Negative | 42,14 | 3,24 | 1,41 | 1 | 0,95 | IND |
Negative | 18,92 | 11,81 | 25,84 | 2 | 0,18 | IND |
(A) Results correspond to indeterminate samples with Multi-HTLV from the development set. The first sample in this group has two positive confirmatory antigens and LR probability (p) less than 0.5, while the second has only one positive GP21-I/II confirmatory antigen but LR probability higher than 0.5 (B) Results correspond to indeterminate samples with Multi-HTLV from the validation set. The first sample in this group has only a positive GP21-I/II confirmatory antigen and LR probability higher than 0.5, while the second has three positive confirmatory antigens but LR probability less than 0.5. CONF, confirmation; Nb, number; LR, Logistic Regression; IND, indeterminate result.