Table 2.
Past medical history and admission characteristics of COVID-19 patients with and without PNX/PNM.
| COVID-19 with PNX/PNM n = 53 |
COVID-19 w/o PNX/PNM n = 106 |
p-Value | |
|---|---|---|---|
| Smoke habit, n (%) | |||
| Never | 30 (56.6%) | 54 (50.9%) | |
| Former | 19 (35.8%) | 43 (40.6%) | n.s. |
| Current | 4 (7.5%) | 9 (8.5%) | |
| Respiratory comorbidities, n (%) | |||
| Asthma | 3 (5.7%) | 3 (2.8%) | n.s. |
| COPD | 3 (5.7%) | 9 (8.5%) | n.s. |
| Chronic interstitial disease | 3 (5.1%) | 1 (0.9%) | n.s. |
| Other Comorbidities, n (%) | |||
| Hypertension | 25 (47.2%) | 61 (57.5%) | n.s. |
| Obesity | 6 (11.3%) | 22 (20.8%) | n.s. |
| Type 2 diabetes | 8 (15.1%) | 24 (22.6%) | n.s. |
| Dyslipidemia | 8 (15.1%) | 30 (28.3%) | n.s. |
| Chronic kidney disease | 2 (3.7%) | 6 (5%) | n.s. |
| Chronic heart disease | 10 (18.8%) | 14 (22.6%) | n.s. |
| Laboratory test on admission, n (%) | |||
| Platelets (×106 cell/mcL) | 216 [148–330] | 237 [181–330] | n.s. |
| n.v. 140,000–440,000 | |||
| Lymphocytes (cell/mcL) | 670 [465–860] | 760 [540–1100] | 0.017 |
| n.v. 1000–4500 | |||
| Neutrophils (cell/mcL) | 5910 [4670–8590] | 6060 [3790–8000] | n.s. |
| n.v. 1800–8000 | |||
| NL ratio | 9.7 [6.4–18.7] | 6.1 [4.2–12.8] | 0.028 |
| n.v. 1.8 | |||
| C-RP (mg/dL) | 9.7 [3.6–14.4] | 8.6 [4.1–19.1] | n.s. |
| n.v. <0.5 mg/dL | |||
| D-dimer (ng/mL) | 1216 [755–1966] | 856 [552–1561] | n.s. |
| n.v. <500 ng/dL | |||
| P/F ratio (mmHg) | 220 [132–291] | 174 [109–257] | n.s. |
| n.v. >400 mmHg | |||
| Days from symptoms onset to hospital admission | 7 [4.5–10] | 5 [2–8] | 0.005 |
| ARDS at admission, n (%) | 45 (84.9%) | 96 (90.5%) | n.s. |
Data are expressed as median [interquartile range] or frequency absolute (relative). p-values are assessed using Mann–Whitney U test, Chi-square, or Fisher’s exact tests as appropriate. n.v.—normal values; n.s.—not significant. COPD: chronic obstructive pulmonary disease.