Table 3.

Cox regression model to predict tumor recurrence, FAS population (n = 502).

Univariate Analysis	Hazard Ratio	95% CI	p-Value
High- vs. intermediate-risk group	1.322	0.968–1.805	0.0783
T1 vs. Ta	1.44	1.019–2.037	0.0009
Primary cis vs. T1	2.609	1.177–5.784
Primary cis vs. Ta	3.758	1.746–8.088
G2 vs. G1	1.088	0.733–1.615	0.1065
G3 vs. G2	1.347	0.927–1.956
G3 vs. G1	1.466	1.003–2.145
Cis vs. no cis	2.551	1.472–4.424	0.0008
Recurrent vs. primary	1.756	1.285–2.399	0.0004
Treatment duration < 4 vs. ≥4 months	1.842	1.321–2.568	0.0003
No maintenance vs. maintenance	1.929	1.307–2.846	0.0009
Previous MMC vs. no	1.611	1.071–2.424	0.0299
Previous BCG vs. no	1.834	1.187–2.84	0.0063
Age ≥ 70 vs. <70 years	1.254	0.917–1.715	0.156
Male vs. female	1.326	0.852–2.061	0.2102
Smoker vs. non-smoker	1.274	0.81–2.004	0.2948
Multiple vs. single tumor	1.220	0.888–1.675	0.2199
Size ≥ 3 vs. <3 cm	1.024	0.724–1.449	0.8895
Multivariate analysis	Hazard Ratio	95% CI	p-value
Recurrent vs. primary	1.828	1.327–2.518	0.0002
Treatment duration < 4 vs. ≥4 months	1.724	1.235–2.407	0.0014
High- vs. intermediate-risk group	1.472	1.071–2.024	0.0171