Table 4.

Cox regression model to predict tumor progression, FAS population (n = 502).

Univariate Analysis	Hazard Ratio	95% CI	p-Value
High- vs. intermediate-risk group	3.076	1.506–6.289	0.002
T1 vs. Ta	3.159	1.596–6.253	0.0008
Primary cis vs. T1	2.078	0.477–9.045
Primary cis vs. Ta	6.563	1.515–28.438
G2 vs. G1	3.03	0.977–9.433	0.0059
G3 vs. G2	1.808	0.877–3.731
G3 vs. G1	5.494	1.865–16.129
Cis vs. no cis	4.424	1.718–11.363	0.0021
Recurrent vs. primary	2.876	1.431–5.784	0.003
Treatment duration < 4 vs. ≥4 months	1.908	0.948–3.84	0.0702
No maintenance vs. maintenance	3.07	1.474–6.396	0.0027
Previous MMC vs. no	2.561	1.199–5.468	0.0151
Previous BCG vs. no	2.717	1.233–5.988	0.0132
Age ≥ 70 vs. <70 years	1.681	0.847–3.339	0.1377
Male vs. female	1.062	0.441–2.557	0.893
Smoker vs. non-smoker	1.011	0.417–2.45	0.9797
Multiple vs. single tumor	1.158	0.591–2.269	0.6684
Size ≥ 3 vs. <3 cm	1.165	0.564–2.403	0.6788
Multivariate Analysis	Hazard Ratio	95% CI	p-value
High- vs. intermediate-risk group	3.891	1.886–8	0.0002
Recurrent vs. primary	3.32	1.613–6.833	0.0011
No maintenance vs. maintenance	2.374	1.125–5.01	0.0233