Figure 11.

Fractalkine levels at 1 and 3 days after laser-induced ocular hypertension (OHT). (a) The fractalkine values obtained in the multiplex assay. The histogram shows the mean levels (±SD) of fractalkine (pg/mg) at days 1 and 3 after laser OHT induction in saffron ocular hypertension eyes (saffron OHT) and saffron-contralateral eyes (saffron-contralateral) as well as in saffron-naïve eyes. (b) Immunohistochemical study of fractalkine expression in saffron OHT eyes one day after unilateral laser-induced OHT. Retinal sections were immunolabeled with antibodies to fractalkine (green) and Iba-1 (red). Merge is denoted by the colour yellow. The arrowhead shows the co-expression of Iba-1 and fractalkine in saffron OHT and saffron-naïve eyes. Abbreviations: OHT (ocular hypertension); Iba-1 (ionized calcium-binding adaptor molecule).