Table 1.
Characteristics of studies evaluating VTE in COVID-19 versus non-COVID-19 cohorts.
| Study | Country | Design | Diagnosis | n | Male Sex (%) | Age (Years) | Main Ward |
|---|---|---|---|---|---|---|---|
| Dalager-Pedersen et al. 2021 [17] | Denmark | Retrospective cohort study (Registry study) | COVID-19 vs. Non-COVID-19 vs. Influenza | 1540 vs. 26,131 vs. 9599 | 56.6 vs. 50.1 | 72.0 (58.0; 81.0) vs. 68.0 (48.0; 78.0) vs. 70.0 (59.0; 80.0) | NA |
| Freund et al. 2020 [18] | France, Spain, Belgium, Italy, Chile, Canada | Retrospective cohort study | COVID-19 vs. non-COVID-19 | 974 vs. 2279 | 48.0 vs. 48.0 | 61.0 ± 19.0 61.0 ± 19.0 |
EW |
| Helms et al. 2020 [19] | France | Prospective with historical control group | COVID-19 vs. Non-COVID-19 ARDS | 77 vs. 145 | 81.8 vs. 77.2 | 68.0 (61.0; 75.0) vs. 72.0 (61.0; 80.0) | ICU |
| Mei et al. 2020 [20] | China | Retrospective cohort study | COVID-19 vs. community-acquired pneumonia | 256 vs. 360 | 51.2 vs. 58.6 | 55.5 (CI 0.5–87.0) vs. 61.0 (CI 15.0–95.0) | NA |
| Pellegrini et al. 2021 [21] | Brazil | Prospective cohort study | COVID-19 vs. non-COVID-19 | 57 vs. 13 | 52.6 vs. 53.8 | 56.0 ± 13.0 vs. 57.0 ± 20.0 | ICU |
| Poissy et al. 2020 [22] | France | Retrospective cohort study | COVID-19 vs. Influenza | 107 vs. 40 | NA | NA | ICU |
| Reider et al. 2020 [23] | Germany | Prospective cohort study | COVID-19 vs. non-COVID-19 | 49 vs. 141 | 61.2 vs. 50.4 | 60.0 (48.5; 71.5) vs. 60.0 (43.5; 76.5) | EW |
| Boyd et al. 2021 [25] | Ireland | Retrospective cohort study | COVID-19 vs. Influenza | 38 vs. 38 | 73.7 vs. 52.6 | 57.9 ± 14.8 vs. 61.0 ± 17.4 | ICU |
| Smilowitz et al. 2021 [26] | United States of America | Retrospective cohort study (registry study) | COVID-19 vs. viral pneumonia | 3334 vs. 954 521 | 50.9 vs. 42.7 | 68.5 vs. 62.8 | NA |
| Burkhard-Koren et al. 2021 [27] | Switzerland | Autoptic study | COVID-19 vs. Influenza | 75 vs. 12 | 72 vs. 25 | 70 (CI 34–96) vs. 46 (CI 1–84) | NA |
| Stals et al. 2021 [12] | The Netherlands | Retrospective cohort study (Registry study) | COVID-19 vs. Influenza | 579 vs. 13,217 (GW) 138 vs. 805 (ICU) |
48.0 vs. 66.0 (GW and ICU) | 69.0 ± 19.0 vs. 67.0 ± 13.0 | GW ICU |
| Doyle et al. 2021 [24] | United Kingdom | Retrospective cohort study | COVID-19 vs. Influenza | 51 vs. 80 | 59.0 vs. 74.5 | 48.3 (38.7; 57.3) vs. 46.1 (35.6; 53.2) | ICU |
Country: country in which the study has been conducted. n: number of patients evaluated in the single study. Age: age is expressed as mean ± Standard deviation, or as mean (95% Confidence interval), or as mean (25th percentile; 75th percentile) depending on the data available in each study. EW: emergency ward. GW: general ward. ICU: intensive care unit. NA: data not available.