Table 4.
Statistically significant differences in relative abundance of bacterial phyla, classes, and orders in studied populations.
| Taxonomic Unit | Relative Abundance in CAD Group | Relative Abundance in Control Group |
p-Value (Adjusted for Sex and Age) |
|---|---|---|---|
| Phyla | |||
| Proteobacteria | 7.4695 (5.1935–9.7455) | 4.6714 (3.4979–5.8449) | 0.032 |
| Bacteroidetes | 33.5334 (30.8517–36.2151) | 37.1957 (35.1636–39.2278) | 0.032 |
| Classes | |||
| Bacteroidetes, Bacteroidia | 33.5334 (30.8517–36.2151) | 37.1957 (35.1636–39.2278) | 0.032 |
| Firmicutes, Bacilli | 4.1117 (2.9382–5.2852) | 1.2206 (0.7898–1.6514) | <0.001 |
| Proteobacteria, Gammaproteobacteria | 6.0816 (3.8101–8.3531) | 3.4073 (2.2397–4.5749) | 0.04 |
| Order | |||
| Actinobacteria, Actinobacteria, Actinomycetales | 0.0281 (0.0164–0.0398) | 0.0135 (0.0095–0.0175) | 0.021 |
| Actinobacteria, Actinobacteria, Micrococcales | 0.0152 (0.0108–0.0196) | 0.0083 (0.0043–0.0123) | 0.021 |
| Bacteroidetes, Bacteroidia, Bacteroidales | 33.4714 (30.7887–36.1541) | 37.1229 (35.0883–39.1575) | 0.033 |
| Firmicutes, Bacilli, Lactobacillales | 3.891 (2.7367–5.0453) | 1.1638 (0.745–1.5826) | <0.001 |
| Proteobacteria, Gammaproteobacteria, Enterobacteriales | 5.4589 (3.1754–7.7424) | 2.5555 (1.4063–3.7047) | 0.026 |
CAD—coronary artery disease group, CI—confidence interval. Mean values together with the 95% confidence intervals of the means are presented.