Table 5.
OTUs with the highest statistical significance that differ between study groups.
| Phylum | Order | Family | Genus | CAD Group (n = 169) |
Control Group (n = 166) |
Adjusted p-Value (FDR) CAD vs. Control |
|---|---|---|---|---|---|---|
| Firmicutes | Clostridiales |
Clostridiales
vadinBB60 group |
Uncultured organism | 0.3797 (0.1217–0.6377) |
0.4296 (0.2595–0.5997) |
<0.001 |
| Fusobacteria | Fusobacteriales | Fusobacteriaceae | Fusobacterium | 0.159 (0.0099–0.3081) |
0.2248 (−0.0595–0.5091) |
<0.001 |
| Firmicutes | Lactobacillales | Lactobacillaceae | Lactobacillus sp., Gut metagenome | 0.1493 (−0.1451–0.4437) |
0.0002 (0–0.0004) |
<0.001 |
| Firmicutes | Clostridiales | Christensenellaceae |
Christensenellaceae
R-7 group |
1.3802 (1.0337–1.7267) |
1.1589 (0.8781–1.4397) |
<0.001 |
| Firmicutes | Lactobacillales | Lactobacillaceae | Lactobacillus sp, Ambiguous taxa | 0.7075 (0.2925–1.1225) |
0.0626 (0.0121–0.1131) |
<0.001 |
| Spirochaetes | Spirochaetales | Spirochaetaceae | Treponema 2 | 0.0699 (−0.0293–0.1691) |
0 (0–0) |
<0.001 |
| Bacteroidetes | Bacteroidales | Prevotellaceae | Prevotellaceae UCG-003 | 0.0434 (−0.0297–0.1165) |
0.0002 (−0.0002–0.0006) |
<0.001 |
| Firmicutes | Clostridiales | Ruminococcaceae | Ruminococcaceae UCG-014 | 4.6675 (3.6518–5.6832) |
3.5864 (2.8496–4.3232) |
<0.001 |
| Bacteroidetes | Bacteroidales | Muribaculaceae | Uncultured bacterium | 0.108 (0.027–0.189) |
0.1365 (0.0385–0.2345) |
<0.001 |
| Proteobacteria | Enterobacteriales | Enterobacteriaceae | Escherichia-Shigella | 4.5528 (2.398–6.7076) |
1.9492 (0.9105–2.9879) |
<0.001 |
CAD—coronary artery disease group, OTUs—operational taxonomic units. Mean values together with the 95% confidence intervals of the means are presented.