Table 6.
The influence of Firmicutes/Bacteroidetes ratio on targeted metabolomics (Biocrates) and biochemical test adjusted for age, sex, CAD status, statins treatment (and) LDL cholesterol concentration.
| Metabolite or Biochemical Test | Group with F/B Ratio ≤ 1.54 (n = 167) |
Group with F/B Ratio > 1.54 (n = 167) |
p Value |
|---|---|---|---|
| Phosphatidylcholine with diacyl residue sum C36:4, μmol/L | 145,308.5375 (95% CI 136,165.244–154,451.831) |
131,525.3521 (95% CI 122,485.2512–140,565.4529) |
0.037 * |
| Phosphatidylcholine with diacyl residue sum C38:5, μmol/L | 46,853.2875 (95% CI 43,791.1361–49,915.4389) |
41,838.3521 (95% CI 39,090.319–44,586.3852) |
0.019 * |
| Phosphatidylcholine with diacyl residue sum C38:6, μmol/L | 68,122.05 (95% CI 62,784.975–73,459.125) |
58,899.7887 (95% CI 54,099.1744–63,700.403) |
0.013 * |
| Phosphatidylcholine with diacyl residue sum C40:6, μmol/L | 26,837.9747 (95% CI 24,778.9683–28,896.9811) |
23,893.6056 (95% CI 21,873.7272–25,913.484) |
0.047 * |
| Phosphatidylcholine with acyl-alkyl residue sum C30:0, μmol/L | 165.6974 (95% CI 153.7441–177.6507) |
209.942 (95% CI 178.6529–241.2311) |
0.008 * |
| Phosphatidylcholine with acyl-alkyl residue sum C34:0, μmol/L | 839.25 (95% CI 782.9649–895.5351) |
958.2254 (95% CI 852.6987–1063.7521) |
0.045 * |
| Phosphatidylcholine with acyl-alkyl residue sum C38:0, μmol/L | 1663.75 (95% CI 1520.5806–1806.9194) |
1465.4225 (95% CI 1353.087–1577.758) |
0.034 * |
| Sphingomyelin with acyl residue sum C24:1, μmol/L | 69,876.9375 (95% CI 65,633.3358–74,120.5392) |
63,321.1268 (95% CI 59,226.511–67,415.7426) |
0.028 * |
| Hematocrit, % | 41.3928 (95% CI 40.8434–41.9422) |
41.8814 (95% CI 41.3236–42.4392) |
0.047 * |
| Hemoglobin, g/dL | 14.1371 (95% CI 13.9429–14.3313) |
14.3413 (95% CI 14.1502–14.5324) |
0.023 * |
| Total cholesterol, mg/dL | 188.9341 (95% CI 181.2163–196.6519) |
171.2455 (95% CI 164.3927–178.0983) |
0.006 ** |
| LDL cholesterol, mg/dL | 118.8796 (95% CI 112.3616–125.3976) |
104.9257 (95% CI 98.4497–111.4017) |
0.026 ** |
CI—confidence interval. Mean values together with the 95% confidence intervals of the means are presented. (* Adjusted for Age, Sex, CAD Status, LDL Cholesterol Concentration, Statins Treatment; ** Adjusted for Age, Sex, CAD Status, Statins Treatment).