TABLE 1.

Geometric mean MICs and ranges of MICs of amphotericin B after 24, 48, and 72 h

Species	No. of isolates	Medium	GMa (range) MIC (μg/ml)
			24 h	48 h	72 h
Aspergillus
A. flavus	27	RPMI	0.9 (0.5–2)	1.17 (1–4)	1.63 (1–4)
		RPMI-2	0.81 (0.25–2)	1.14 (1–4)	1.43 (1–4)
		AM3	0.57 (0.5–1)	1.03 (0.5–4)	1.33 (0.5–4)
A. fumigatus	26
General isolates	24	RPMI	0.87 (0.5–1)	1.33 (1–2)	2.18 (1–4)
		RPMI-2	0.73 (0.5–1)	1.3 (1–4)	1.94 (1–4)
		AM3	0.36 (0.25–1)	0.65 (0.25–1)	1.09 (0.5–2)
Itraconazole-resistant isolates	2	RPMI	1 (1)	1.41 (1–2)	1.41 (1–2)
		RPMI-2	1 (1)	1.41 (1–2)	2.83 (2–4)
		AM3	0.25 (0.25)	0.71 (0.5–1)	1 (1)
A. niger	17	RPMI	0.33 (0.125–1)	0.54 (0.25–1)	0.75 (0.25–2)
		RPMI-2	0.26 (0.06–0.5)	0.32 (0.125–1)	0.54 (0.25–1)
		AM3	0.09 (0.03–0.25)	0.29 (0.125–0.5)	0.44 (0.125–1)
A. terreus	9	RPMI	0.63 (0.25–1)	2.33 (0.5–>4)	4.32 (1–>4)
		RPMI-2	0.63 (0.25–1)	1.85 (0.5–>4)	3.17 (0.5–>4)
		AM3	0.68 (0.125–1)	2.94 (0.5–>4)	4.67 (0.5–>4)
A. nidulansb	3	RPMI		1 (1)	2 (2)
		RPMI-2		2 (2)	2 (2)
		AM3		0.5 (0.5)	1 (1)
Fusarium
F. solani	18	RPMI	1.85 (1–4)	3.3 (1–>4)	4.39 (2–>4)
		RPMI-2	1.53 (0.5–4)	2.83 (1–>4)	3.17 (1–>4)
		AM3	2 (0.5–>4)	2.83 (1–>4)	3.56 (1–>4)
F. oxysporum	4	RPMI	2.38 (2–4)	3.36 (2–4)	4 (4)
		RPMI-2	2 (2)	2.83 (2–4)	4 (4)
		AM3	2 (1–2)	5.66 (4–>4)	6.73 (4–>4)

^aGM, Geometric mean. 

^bNo growth at 24 h.