Table 1.
Clinical Characteristics of 61 male patients with SARS-CoV-2 infection.
| Characteristics | Non-ICU (n = 38) | ICU (n = 23) | P value |
|---|---|---|---|
| Demographics | |||
| Median (interquartile range) age (years) | 52 (36.8 ∼ 61.3) | 64 (51.8 ∼ 74) | 0.001 |
| Underlying conditions, n (%) | |||
| Any | 16 (42.1) | 17 (73.9) | 0.016 |
| Hypertension | 10 (26.3) | 15 (65.2) | 0.003 |
| Diabetes mellitus | 5 (13.2) | 5 (21.7) | 0.603 |
| Heart disease | 3 (7.9) | 2 (8.7) | 1.000 |
| Lung disease | 0 (0) | 3 (13.0) | 0.049 |
| Liver disease | 1 (2.6) | 2 (8.7) | 0.551 |
| Renal disease | 0 (0) | 1 (4.3) | 0.377 |
| Immune compromise | 0 (0) | 1 (4.3) | 0.377 |
| Symptoms, n (%) | |||
| Fever | 36 (94.7) | 21 (91.3) | 0.628 |
| Cough | 16 (42.1) | 13 (56.5) | 0.275 |
| Sputum | 6 (15.8) | 10 (43.5) | 0.017 |
| Diarrhoea | 8 (21.1) | 7 (30.4) | 0.410 |
| Fatigue | 3 (7.9) | 6 (26.1) | 0.117 |
| Chest distress | 6 (15.8) | 2 (8.7) | 0.698 |
| Nausea | 1 (2.6) | 1 (4.3) | 1.000 |
| Vomiting | 2 (5.3) | 0 (0) | 0.522 |
| Treatment, n (%) | |||
| Gammaglobulin | 18 (47.4) | 20 (87.0) | 0.002 |
| Glucocorticoids | 27 (71.1) | 23 (1 0 0) | 0.012 |
| Antivirals | 38 (1 0 0) | 23 (1 0 0) | NA |
| Invasive mechanical ventilation | 0 (0) | 11 (47.8) | <0.001 |
| ECMO | 0 (0) | 8 (34.8) | <0.001 |
| Laboratory Indicators, median [IQR] | |||
| Neutrophils count, ×109/L | 3.6 (2.5 ∼ 6.6) | 7.9 (3.6 ∼ 12) | 0.004 |
| Lymphocyte count, ×109/L | 0.9 (0.6 ∼ 1.3) | 0.6 (0.5 ∼ 0.9) | 0.006 |
| Hemoglobin, g/L | 148 (137 ∼ 155) | 131 (121 ∼ 151) | 0.006 |
| Platelet count, ×109/L | 184 (138.5 ∼ 234.5) | 176 (148 ∼ 193) | 0.401 |
| PaO2, mmHg | 87.0 (80.2 ∼ 102.8) | 84.9 (69.3 ∼ 93.6) | 0.297 |
| Albumin, g/L | 41.5 (36.4 ∼ 44.6) | 34.8 (31.3 ∼ 40.9) | 0.004 |
| Aspartate aminotransferase, IU/L | 22.5(18 ∼ 34) | 27 (19 ∼ 42) | 0.284 |
| Creatinine, μmol/L | 83 (70.5 ∼ 91.3) | 90 (72 ∼ 107) | 0.094 |
| Creatine kinase, IU/L | 77 (62.5 ∼ 115) | 105 (60 ∼ 296) | 0.134 |
| Lactate dehydrogenase, IU/L | 247 (214 ∼ 317) | 301 (242 ∼ 386) | 0.067 |
| Fibrinogen, g/L | 4.4 (3.4 ∼ 5.6) | 4.5 (4.1 ∼ 5.5) | 0.553 |
| D-dimer, ug/IFEU | 320 (176.5 ∼ 544) | 440.5 (281.8 ∼ 797) | 0.063 |
| C-reactive protein, mg/L | 24.3 (10.9 ∼ 45.2) | 46.4 (26.8 ∼ 88.1) | 0.012 |
| IL-6, pg/mL | 22 (8.7 ∼ 44.5) | 47.2 (24 ∼ 84.5) | 0.008 |
| IL-10, pg/mL | 3.9 (2.7 ∼ 7.5) | 6.7 (4.8 ∼ 8.6) | 0.024 |
| Testosterone, nmol/L | 6.7 (4.2 ∼ 8.7) | 3.7 (1.5 ∼ 4.7) | 0.012 |
| PSI index | 56.5 (51 ∼ 66) | 72 (60 ∼ 86) | 0.002 |