Table 3.
Receiver operating characteristic (ROC) curve parameters for the serum testosterone level and other biomarkers on the second week of admission in COVID-19 male patients.
Variable | Cutoff value | Youden index | Sensitivity (%) | Specificity (%) | AUC | 95% CI | P value |
---|---|---|---|---|---|---|---|
Testosterone | 3.26 | 0.621 | 65.0 | 97.1 | 0.876 | 0.759 ∼ 0.949 | <0.001 |
Neutrophils count | 5.25 | 0.514 | 100.0 | 51.4 | 0.725 | 0.590 ∼ 0.836 | <0.001 |
Lymphocyte count | 0.56 | 0.429 | 71.4 | 71.4 | 0.756 | 0.623 ∼ 0.861 | <0.001 |
C-reactive protein | 32.55 | 0.406 | 50.0 | 90.6 | 0.727 | 0.585 ∼ 0.841 | 0.002 |
IL-6 | 22.21 | 0.389 | 72.2 | 66.7 | 0.715 | 0.566 ∼ 0.836 | 0.006 |
AUC: Area under the ROC curve; CI: Confidence Interval.