Table 2.

Pooled Data of Mortality of COVID-19 Patients on VV-ECMO and of Other Categorical and Continuous Variables

Categorical Variables
Variable	No of Studies	Patients, n/N	Proportion	95% CI	Heterogeneity	Risk of Bias (Egger's test)
Mortality	102	1,508/3,793	0.39	0.34-0.43	I2 53%; p < 0.01	-
ECMO/COVID-19 cases	65	4,044/58,472	0.07	0.05-0.09	I2 97%; p < 0.01	+
Male sex	77	2,606/3,455	0.71	0.67-0.74	I2 23%; p = 0.04	+
Continuous variables
Variable	No of Studies	Patients	Mean, d	95% CI	Heterogeneity	Risk of Bias
ECMO Duration	31	3,176	15	13.34-27.62	I2 98%; p < 0.01	+
MV prior ECMO	26	1,747	4.25	3.32-5.18	I2 99%; p < 0.01	+

NOTE. Data are presented as categorical and continuous variables. Categorical variables are expressed as proportions and 95% CI according to the random effect model single outcome meta-analysis; continuous variables are indicated as means and 95% CI.

Abbreviations: ECMO, extracorporeal membrane oxygenation; MV, mechanical ventilation.