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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Ophthalmology. 2021 Apr 20;128(12):1699–1707. doi: 10.1016/j.ophtha.2021.04.017

Table 2.

Incidence of herpes zoster per 100 000 person-years by demographic characteristics and recombinant zoster vaccination status from 2018 to 2019

Unvaccinated Vaccinated
Number of Cases Number of Person-Years Incidence Rate (95% CI) Number of Cases Number of Person-Years Incidence Rate (95% CI)
Overall
5 654 7 374 053 76.7 (74.7, 78.7) 30 117 517 25.5 (17.4, 35.8)
Age group, y a
50–59 1 226 2 343 779 52.3 (49.4, 55.3) 0 2 142 0.0
60–79b 3 282 4 051 347 81.0 (78.3, 83.8) > 19 90 069 > 21.1 (13.0, 32.1)
80+ 1 146 978 927 117.1 (110.4, 124.0) <11 25 306 <43.5 (22.6,74.4)
Sex
Male > 2254 3 510 499 > 64.2 (61.6, 66.9) > 19 49 190 > 38.6 (23.8, 58.7)
Female 3 389 3 858 797 87.8 (84.9, 90.8) <11 67 947 < 16.2 (8.4, 27.7)
Unknownc < 11 4 757 < 231.2 (120.1, 395.9) 0 380 0.0
a

OptumLabs requires cell counts <11 to be reported as <11 rather than reporting true values in order to protect patient privacy. In order to prevent back calculation, the value in a corresponding cell of the same subgroup is lowered and reported with a greater than sign to ensure that the total case count within the subgroup stays the same. Each affected subgroup’s HZO incidence rate was reported with greater than and less than signs. Numbers are not reported for race/ethnicity subgroups due to the cell suppression policy.

b

Incidence rates for age group 60–69 and 70–79 have been combined together to protect patient privacy due to low cell counts.

c

The unknown sex category includes individuals with either unknown or missing sex.