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. 2021 Oct 20;26:1130–1147. doi: 10.1016/j.omtn.2021.10.017

Table 3.

Relationship between circRNAs level and clinicopathologic characteristics in PCa

circRNA name CircBase ID Host gene Cutoff value Internal reference Dysregulation Number of patients
circ_SLC19A1 hsa_circ_0062019 SLC19A1 18S rRNA upregulated 173
circ_0057558 hsa_circ_0057558 SLC19A1 18S rRNA upregulated 173
circAR3 AR GAPDH upregulated 91
circAMOTL1L hsa_circ_000,350 PCHAD8 GAPDH Downregulated 97
circFOXO3 hsa_circ_0006404 FOXO3 MEL β-actin upregulated 53
circABCC4 hsa_circ_0030586 ABCC4 GAPDH & U6 upregulated 47
circ_ITCH ITCH MEL GAPDH & U6 downregulated 52
circ-MTO1 hsa_circ_0076979 MTO1 MEL GAPDH downregulated 298
hsa_circ_0001206 hsa_circ_0001206 CRKL β-actin downregulated 50
hsa_circ_0009061 hsa_circ_0009061 KDM1A β-actin downregulated 50
circRNA17 hsa_circ_0001427 PDLIM5 GAPDH downregulated 39
circHIPK3 hsa_circ_0000284 HIPK3 GAPDH or U6 upregulated 26
circ_ITCH ITCH MEL GAPDH downregulated 324
circ_0088233 hsa_circ_0088233 PAPPA GAPDH upregulated 46
circMBOAT2 hsa_circ_0007334 MBOAT2 GAPDH upregulated 112
circ-0016068 hsa_circ_0016068 BTG2 MEL GAPDH upregulated 42
circFMN2 hsa_circ_0005100 FMN2 MEL 18S rRNA upregulated 88
circ_HIPK3 HIPK3 upregulated 45
hsa_circ_0007494 hsa_circ_0007494 ROCK2 GAPDH downregulated 49
circ-LARP4 LARP4 GAPDH downregulated 55
hsa_circ_0000735 hsa_circ_0000735 P2RX1 MEL GAPDH upregulated 50
Age Tumor size Gleason score PSA T stage LNM Number of tumors DM Invasion Surgical margin DFS OS Reference Year
Yes yes yes yes Xia et al.59 2018
No yes no no Xia et al.59 2018
yes no yes no Luo et al.169 2019
No yes yes Yang et al.65 2019
No yes no Kong et al.86 2020
No yes yes yes yes Huang et al.75 2019
No yes yes yes no no yes Wang et al.97 2019
No no no yes yes no yes yes Hu et al.104 2020
No yes no yes no Song et al.66 2019
No no no yes no Song et al.66 2019
yes Wu et al.94 2019
yes Chen et al.78 2019
No no no yes yes yes yes yes Huang et al.170 2019
No yes Deng et al.63 2020
No yes no yes no yes Shi et al.85 2020
No yes yes yes yes Li et al.64 2020
No yes yes yes Shang et al.67 2020
No yes no no Liu et al.90 2020
No yes no yes no yes Zhang et al.101 2020
yes Weng et al.105 2020
yes Gao et al.82 2020

MEL, median expression level.