Table 2.
Baseline invasive haemodynamic parameters according to MAP/RAP ratio before the MitraClip procedure.
| All Patients n = 145 |
MAP/RAP < 7.13 n = 74 |
MAP/RAP ≥ 7.13 n = 71 |
p-value | |
|---|---|---|---|---|
| MAP/RAP Ratio IQR |
7.07 (5.20–10.58) | 5.25 (4.29–5.94) | 10.71 (8.60–16.83) | <0.001 |
| HR mean beats/min ± SD |
77 ± 14.77 | 77 ± 13.1 | 77 ± 16.4 | 0.86 |
| RR syst. mean mmHg ± SD |
127 ± 26.0 | 124 ± 25.7 | 130 ± 26.1 | 0.18 |
| RR diast. mean mmHg ± SD |
71 ± 12.77 | 71 ± 12.6 | 70 ± 13.1 | 0.99 |
| RR mean median mmHg (IQR) |
88 (81–101) | 88 (82–97) | 89 (81–103) | 0.14 |
| PASP mean mmHg ± SD |
60 ± 16.3 | 64.9 ± 15.4 | 54 ± 15.4 | <0.001 |
| PAP mean mean mmHg ± SD |
39 ± 10.6 | 44 ± 10.2 | 34 ± 8.8 | <0.001 |
| PCWP mean mmHg ± SD |
29 ± 10.6 | 34 ± 9.9 | 23 ± 8.7 | <0.001 |
| V-wave mean mmHg ± SD |
42 ± 15.7 | 49 ± 13.1 | 35 ± 15.1 | <0.001 |
| PAP diast. mean mmHg ± SD |
25 ± 9.3 | 29 ± 9.2 | 21 ± 7.5 | <0.001 |
| RAP mean mean mmHg ± SD |
13 ± 6.7 | 18 ± 5.1 | 8.0 ± 3.4 | <0.001 |
| CO median l/min (IQR) |
3.5 (2.9–4.2) | 3.4 (2.7–4.1) | 3.5 (3.0–4.3) | 0.24 |
| CI mean l/min/m2 ± SD |
2.0 ± 0.60 | 1.8 ± 0.42 | 2.1 ± 0.71 | 0.007 |
| PVR mean dyn*s*cm−5 ± SD |
279 ± 201 | 290 ± 216 | 267 ± 184 | 0.5 |
| TVR mean dyn*s*cm−5 ± SD |
1786 ± 617 | 1713 ± 604 | 1849 ± 625 | 0.17 |
| CFP mean mmHg ± SD |
0.48 ± 0.24 | 0.58 ± 0.24 | 0.37 ± 0.18 | <0.001 |
| PAPi median (IQR) |
2.69 (1.9–4.0) | 2.0 (1.5–2.6) | 4.0 (3.0–5.9) | <0.001 |
| LVSWi mean g/m−1/m2 ± SD |
22.0 ± 10.8 | 18.0 ± 7.6 | 26.2 ± 12.1 | <0.001 |
| RVSWi mean g/m−1/m2 ± SD |
8.9 ± 4.2 | 8.1 ± 3.3 | 9.8 ± 4.8 | 0.01 |
| TPG median mmHg (IQR) |
11 (6–15) | 11 (6–15) | 11 (6–15) | 0.75 |
| PA compliance median ml/mmHg (IQR) |
1.4 (1.0–1.9) | 1.3 (0.9–1.7) | 1.6 (1.1–2.2) | 0.02 |
| SV median ml/beat (IQR) |
46 (36–58) | 45 (35–57) | 47 (38–63) | 0.25 |
| SVi median ml/m2/beat (IQR) |
24.9 (19.6–29.8) | 23.5 (18.2–28.5) | 25.5 (21.4–33.5) | 0.04 |
| LVEDV median ml (IQR) |
127 (101–186) | 138 (106–183) | 122 (100–187) | 0.41 |
CFP: cardiac filling pressures; CI: cardiac index; CO: cardiac output; DPG: diastolic pulmonary gradient; HR: heart rate; IQR: interquartile range; LVEDV: left ventricular enddiastolic diameter; LVSWi: left ventricular stroke work index; PA: pulmonary artery; PAPdiast.: pulmonary artery diastolic pressure; PAPi: pulmonary artery pulsatility index; PAP mean: mean pulmonary artery pressure; PASP: pulmonary artery systolic pressure; PCWP: postcapillary wedge pressure; PVR: pulmonary vascular resistance; RAP: right atrial pressure; RR diast.: systemic artery diastolic pressure; RR mean: systemic artery mean pressure; RR syst.: systemic artery systolic pressure; RVSWi: right ventricular stroke work index; SV: stroke volume; SVi: stroke volume index; TPG: transpulmonary gradient.