Table 3.
Cox Proportional hazards models for incident parkinson disease by visual impairment status.
| VI Status | Age-, Gender- and Ethnicity-Adjusted Model |
Multivariable Model a |
||||||
|---|---|---|---|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | |||||
| Main analysis | ||||||||
| VI status | ||||||||
| None | 1 [Reference] | – | 1 [Reference] | – | ||||
| VI | 2·13 (1·27–3·56) | 0·004 | 2·28 (1·29–4·05) | 0·005 | ||||
| Sensitivity analysis Ib | ||||||||
| VI status | ||||||||
| None | – | – | 1 [Reference] | – | ||||
| VI | – | – | 2.28 (1·29–4·04) | 0·005 | ||||
| Sensitivity analysis IIc | ||||||||
| VI status | ||||||||
| None | 1 [Reference] | – | 1 [Reference] | – | ||||
| VI | 1·79 (1·05–3·03) | 0·031 | 1·93 (1·07–3·48) | 0·030 | ||||
VI = visual impairment; PD = Parkinson's disease; HR = hazard ratio; CI = confidence interval.
Cox proportional hazards regression models adjusted for age, gender, race/ethnicity, Townsend deprivation index, smoking status, drinking status, obesity, physical activity, history of stroke, history of diabetes, history of hypertension, psychotropic medications and cognitive impairment.
Cox proportional hazards regression models adjusted for age, gender, race/ethnicity, Townsend deprivation index, smoking status, drinking status, obesity, physical activity, history of stroke, history of diabetes, history of hypertension, psychotropic medications, cognitive impairment and depression.
Excluding incident PD diagnosed in the year immediately following baseline assessment.