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. 2021 Nov 6;42:101189. doi: 10.1016/j.eclinm.2021.101189

Table 3.

Cox Proportional hazards models for incident parkinson disease by visual impairment status.

VI Status Age-, Gender- and Ethnicity-Adjusted Model
Multivariable Model a
HR (95% CI) P-value HR (95% CI) P-value
Main analysis
VI status
None 1 [Reference] 1 [Reference]
VI 2·13 (1·27–3·56) 0·004 2·28 (1·29–4·05) 0·005
Sensitivity analysis Ib
VI status
None 1 [Reference]
VI 2.28 (1·29–4·04) 0·005
Sensitivity analysis IIc
VI status
None 1 [Reference] 1 [Reference]
VI 1·79 (1·05–3·03) 0·031 1·93 (1·07–3·48) 0·030

VI = visual impairment; PD = Parkinson's disease; HR = hazard ratio; CI = confidence interval.

a

Cox proportional hazards regression models adjusted for age, gender, race/ethnicity, Townsend deprivation index, smoking status, drinking status, obesity, physical activity, history of stroke, history of diabetes, history of hypertension, psychotropic medications and cognitive impairment.

b

Cox proportional hazards regression models adjusted for age, gender, race/ethnicity, Townsend deprivation index, smoking status, drinking status, obesity, physical activity, history of stroke, history of diabetes, history of hypertension, psychotropic medications, cognitive impairment and depression.

c

Excluding incident PD diagnosed in the year immediately following baseline assessment.