Table 1.
Oximetry values in NC and CAP sperm from wild-type and CatSper KO mice. Coupling efficiency = Oligomycin-sensitive respiration/basal respiration; RCR = Maximal respiration in the presence of FCCP/ATP turnover; spare respiratory capacity = Maximal respiration in the presence of FCCP/Basal Respiration.
| Index | Wild-type |
CatSper KO |
||||||
|---|---|---|---|---|---|---|---|---|
| Mean | SD | P-Value | Mean | SD | p-value | |||
| Coupling efficiency | NC | 0.48 | 0.18 | 0.009 | NC | 0.37 | 0.06 | 0.1 |
| CAP | 0.56 | 0.20 | CAP | 0.32 | 0.11 | |||
| RCR | NC | 3.5 | 1.9 | 0.012 | NC | 2.12 | 0.50 | 0.84 |
| CAP | 5.8 | 4.8 | CAP | 2.05 | 0.70 | |||
| Spare Respiration Capacity | NC | 1.5 | 0.8 | 0.96 | NC | 1.34 | 0.36 | 0.72 |
| CAP | 1.5 | 0.9 | CAP | 1.43 | 0.61 | |||