Table 1:
Sp6 tooth-enriched genes.
| Gene Symbol | Gene Name | Sp6 Peak Locationa |
|---|---|---|
| Ambn | Ameloblastin | −172 |
| Amelx | Amelogenin | −5499 |
| Asxl3 | Sex combs like | −4873 |
| Bmp7 | Bone morphogenetic protein 7 | + 1314 |
| Cldn1 | Claudin 1 | +3125 |
| Col11a2 | Collagen 11a2 | −446 |
| Cxadr | Coxsackie adeno receptor | −1520 |
| Dlx2 | Dlx homeobox 2 | −1538 |
| Dlx3 | Dlx homeobox 3 | +8935 |
| Dlx4 | Dlx homeobox 4 | +425 |
| Dlx5 | Dlx homeobox 5 | −124 |
| Dspp | Dentin sialo phospho protein | −339 |
| Dlx6os1 | Dlx6 opposite strand | −562 |
| Edg3 | G-protein-receptor 3 | +971 |
| Enam | Enamelin | −168 |
| Fras1 | Fraser syndrome 1 homolog | +2274 |
| Gal3st4 | Galactose-3-O-sulfotransferase 4 | −6722 |
| Hapln1 | Hyaluronan and proteoglycan binding link protein 1 | +9622 |
| Ibsp | Integrin binding sialoprotein | −221 |
| Klk4 | Kallikrein 4 | −838 |
| Maf | Avian fibrosarcoma homolog | −886 |
| Mmp14 | Matrix metallopeptidase 14 | −264 |
| Mmp20 | matrix metallopeptidase 20 | −135 |
| Msx2 | Msx2 homeo box | −203 |
| Nedd4 | Neural down-regulated gene 4 | +4854 |
| Papln | Sulfated glycoprotein | +749 |
| Phex | Phosphate regulating gene | −270 |
| Pitx2 | Paired-like homeodomain | +460 |
| Rnd3 | Rho family GTPase 3 | +23 |
| Shh | Sonic hedgehog | +28 |
| Slc39a8 | solute carrier 39 | +2372 |
| Sox4 | SRY-box4 | −17 |
| Sp6 | Sp6 | −2115 |
| Sp7 | Sp7 | −84 |
| Trp63 | Transformation related protein 63 | −28 |
| Vangl2 | Van gogh like-2 | −1097 |
| Wnt6 | wingless-6 | −7650 |
a
Numbers denote the location of the Sp6 target peak in either the promoter (negative number) or the first intron (positive number).