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Structures and ZVpro inhibitory activities of compounds 1−13 with a para-tert-butylphenyl group.a
| Cpd # | Structure | IC50 (μM) | Cpd # | Structure | IC50 (μM) |
|---|---|---|---|---|---|
| 1 |
|
4.5 | 8 |
|
1.3 |
| 2 |
|
11.0 | 9 |
|
9.1 |
| 3 |
|
14.6 | 10 |
|
3.1 |
| 4 |
|
>50 | 11 |
|
3.2 |
| 5 |
|
>50 | 12 |
|
2.1 |
| 6 |
|
7.0 | 13 |
|
5.1 |
| 7 |
|
5.0 |
Standard errors of all IC50 values are less than 30%.
