Table 4.
Structures and ZVpro inhibitory activities of 5-substituted indole-2-carboxamide compounds 33-46.a
|
|||||
|---|---|---|---|---|---|
| Cpd # | R5 | IC50 (μM) | Cpd # | R5 | IC50 (μM) |
| 33 |
|
>50 | 40 |
|
11.4 |
| 34 |
|
37.0 | 41 |
|
3.4 |
| 35 |
|
6.0 | 42 |
|
33.0 |
| 36 |
|
9.5 | 43 |
|
8.8 |
| 37 |
|
0.87 | 44 |
|
9.2 |
| 38 |
|
1.1 | 45 |
|
40.2 |
| 39 |
|
4.7 | 46 |
|
30.5 |
Standard errors of all IC50 values are less than 30%.