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. Author manuscript; available in PMC: 2022 Dec 5.

Published in final edited form as: Eur J Med Chem. 2021 Aug 14;225:113767. doi: 10.1016/j.ejmech.2021.113767

Table 5.

Structures and ZVpro inhibitory activities of 6-substituted indole-2-carboxamide compounds 47-66.^a


Cpd #	R⁶	IC₅₀ (μM)	Cpd #	R⁶	IC₅₀ (μM)
47	H	24.6	57		5.6
48		9.4	58		7.9
49		14.4	59		9.8
50		1.0	60		19.7
51		3.2	61		27.2
52		3.2	62		2.2
53		7.1	63		21.0
54		3.1	64		0.99
55		45.6	65		6.4
56		1.6	66		0.32

^a

Standard errors of all IC₅₀ values are less than 30%.