FIGURE 1.

Contrast sensitivity and visual acuity as measured using Optometry ∼2 months after impact. (A) The contrast sensitivity thresholds for both eyes were significantly higher in impact-vehicle mice than in sham-vehicle mice. Mice treated with raloxifene were similar to sham and improved over impact-vehicle mice. (B) Visual acuity for impact-vehicle mice was somewhat diminished compared to sham mice, but the reduction was not statistically significant. Mice treated with raloxifene showed a smaller reduction in visual acuity than the impact-vehicle mice. Data are pooled for the two eyes. Errors bars are SEMs. Animal numbers: 21 sham-vehicle mice, 26 impact-vehicle mice, 22 impact-ral5 mice, and 14 impact-ral10 mice.