Figure 2.

Logistic regression models on the interaction between IL6 and childhood adversities on history of lifetime suicide attempts yielded three significant clumps (one for additive and two for dominant models), surviving correction for multiple testing. In the additive model, a clump containing three SNPs emerged with rs2069835 as the top SNP and the minor C allele as a protective allele (p = 0.0004) (A). In the dominant model, a clump containing 4 SNPs with rs 2069835 as the top SNP and the minor C allele as a protective allele (p = 0.0004) (B), and another clump containing 3 SNPs, with rs1880241 as the top SNP and the minor G allele as a risk allele (p = 7.08 × 10⁻⁵) (C) was identified. The figure was generated for illustration purposes using R.