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. 2021 Oct 29;12:775506. doi: 10.3389/fphar.2021.775506

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Copyright © 2021 Xiang, Chen, Wang, Zhai, Sun, Feng, Duan, Zhang, Pan, Yan, Jin, Gao, Wen, Ma, Liu, Wang, Wu, Xie and Sui.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Erianin suppressed tumor growth by inducing ferroptosis in vivo. (A) Representative image of mice and xenograft tumors at the endpoint of experiment. (B) The average tumor volume from different groups. Values are shown as mean ± SD, **p < 0.01. (C) The average mice weight from different groups. Values are shown as mean ± SD. (D) The expression of Ki67, GPX4, SLC40A1 and xCT were detected by IHC.