Table 1.
Patient characteristics
| Kenya | Sudan | Ethiopia | India | Total | |
|---|---|---|---|---|---|
| Subjects (n) | 16 | 16 | 42 | 454 | 528 |
| Male [n (%)] | 13 (81) | 13 (81) | 34 (81) | 296 (65) | 356 (67) |
| Age, years [mean (range)] | 23.1 (15–45) | 25.4 (12–40) | 19.9 (8–60) | 22.5 (5–54) | 22.4 (5–60) |
| Paediatric patientsa [n (% of total)] | 3 (19) | 3 (19) | 18 (43) | 190 (42) | 214 (41) |
| Body weight, kg [mean (range)]b | 47.3 (37–56) | 49.1 (34–73) | 39.4 (15–62) | 35.8 (11–68) | 36.8 (11–73) |
| Creatinine, µmol/L [mean (range)]b | 95.3 (79.6–134) | NA | 79.5 (44.2–115) | NA | 83.8 (44.2–134) |
| eGFR, mL/min/1.73 m2 [mean (range)]b | 110 (62–147) | NA | 143 (72.6–288) | NA | 134.2 (62–288) |
| Albumin, g/Lb | 23.8 (7–33) | 27.4 (21–40) | 28.0 (13–40) | NA | 27.0 (7–40) |
eGFR estimated glomerular filtration rate, NA not applicable
aPatients < 18 years of age
bAt baseline