Table 4.
Paromomycin exposure by dose and country
Dose | Country | AUCτ,SS [µg·h/mL]a |
---|---|---|
15 mg/kg | Kenya | 188.4 (151.4–233.5) |
Sudan | 149.4 (137.6–170.8) | |
Ethiopia | 230.1 (146.3–591.2) | |
India | 97.26 (80.83–123.4) | |
20 mg/kg | Kenya | 215.0 (142.8–337.0) |
Sudan | 287.8 (244.5–341.6) | |
Ethiopia | 235.9 (117.7–391.2) |
AUCτ,SS area under the plasma concentration-time curve for 24 h at steady-state, determined on the last day concentrations were measured, IQR interquartile range
aMedian (IQR)