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. 2021 Jun 9;60(11):1463–1473. doi: 10.1007/s40262-021-01036-8

Table 4.

Paromomycin exposure by dose and country

Dose Country AUCτ,SS [µg·h/mL]a
15 mg/kg Kenya 188.4 (151.4–233.5)
Sudan 149.4 (137.6–170.8)
Ethiopia 230.1 (146.3–591.2)
India 97.26 (80.83–123.4)
20 mg/kg Kenya 215.0 (142.8–337.0)
Sudan 287.8 (244.5–341.6)
Ethiopia 235.9 (117.7–391.2)

AUCτ,SS area under the plasma concentration-time curve for 24 h at steady-state, determined on the last day concentrations were measured, IQR interquartile range

aMedian (IQR)