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. 2021 Jul 16;77(12):1875–1885. doi: 10.1007/s00228-021-03182-1

Table 3.

Details regarding participants reporting drug-related psychiatric health aspects over the bariatric surgery procedure that, in retrospect, were temporarily associated with a substantial* change in the dose-adjusted drug concentration

Case No Surgical procedure Substance Baseline Post-surgery Health consequences related to changed drug concentrations
Drug dose Concentration Day Drug dose Concentration
1 GBP Citalopram 10 mg 137 nmol/L  +252 10 mg 69 nmol/L Reported increased dose 3–4 weeks before the final sampling because of psychiatric symptoms
 +374 20 mg 158 nmol/L
2 GBP Citalopram 10 mg 89 nmol/l  +178 10 mg 42 nmol/L Reported increased dose 2 weeks before the final sampling because of depressive symptoms
 +386 20 mg 90 nmol/L
3 GBP Mirtazapine 15 mg 96 nmol/L  +68 15 mg 30 nmol/L Reported that sertraline had been switched to escitalopram after the first post-surgery sampling without beneficial effects, changed back to sertraline
 +368 30 mg 203 nmol/L
Sertraline 200 mg 130 nmol/L  +68 200 mg 66 nmol/L
 +368 200 mg 78 nmol/L
4 Sleeve Mirtazapine 30 mg 140 nmol/L 213 30 mg 87 nmol/L Reported increased dose 2 months before the final sampling because of the psychiatric condition
393 45 mg 119 nmol/L

GBP gastric bypass

*Doubled/halved