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. 2021 Oct 29;12:764245. doi: 10.3389/fgene.2021.764245

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Copyright © 2021 Lin, Zhang, Lin and Peng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The corrected genes of High Mobility Group Box 1 (HMGB1) in ACC and GSEA results. The top 50 genes significantly (A) positively and (B) negatively correlated with HMGB1 in ACC (LinkedOmics). The top 20 significantly enriched (C) GO-BP, (D) GO-CC, (E) GO-MF, and (F) KEGG pathway terms of HMGB1 correlated genes based on GSEA. A bar represents a normalized enrichment score for a term, which in orange or blue represents negatively or positively enriched, respectively.