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. 2021 Nov 11;11:22099. doi: 10.1038/s41598-021-01568-w

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Hemolysis quantification of RBCs after passage through the microdevices. (A) Different conditions of the hemolysis assay with a picture of the 96-well plate containing the supernatants of the different samples. Data correspond to one representative experiment. (B) Hemolysis quantification of RBCs. Plots show the mean and the standard error of supernatant absorbance values of uRBCs and P.f.-RBCs that passed through model 1 and model 2. Data correspond to all experiments performed through the study. Statistical significance was determined using the Kruskal–Wallis test. Dunn's multiple comparisons test showed the following results (****p ≤ 0.0001; ***p ≤ 0.001; **p ≤ 0.01; *p ≤ 0.05).